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  王海峰,博士,讲师,硕士生导师

  地址:湖北省武汉市东湖新技术开发区光谷一路206

  邮编:430205

                                   E-mail: skytacle@139.com


教育背景

2013.9-2017.7,复旦大学,化学系,博士

2005.9-2008.7,西北师范大学,化学化工leyu乐鱼,硕士

工作履历

2019.12-至今,武汉工程大学,化工与制药leyu乐鱼,讲师

2017.7-2019.11, 周口师范leyu乐鱼,化学化工leyu乐鱼,讲师

2008.7-2013.7,制药企业,从事新药开发和药物合成工艺研发

研究领域

(1)天然产物和手性药物的合成研究;

(2)基于微通道连续流动化学技术的药物合成工艺研究;

(3)卡宾化学新反应研究

科研项目

1.湖北省自然科学基金一般面上项目, 主持

2.华理工大学江西省合成化学重点实验室开放基金项目,主持

3.湖北省教育厅科学研究计划指导性项目,主持

4.河南省科技厅科技攻关项目,主持

学术成果

代表性论文:

1. Jingru Jin, Chunyan Li, Rui Wang, Zhimin Xia, Qiongjiao Yan, Wei Wang, ShuangXi Gu, Haifeng Wang*, and Fener Chen*. Chemodivergent Synthesis of Sulfonamide and Sulfones from N-Tosylhydrazones by Switching Catalyst and Temperature. Org. Lett. leyu乐鱼, 25, 32, 6012-6017 .

2. Chunyan Li, Rui Wang, Li Huang, Jiale Chen, Jingru Jin, Qiongjiao Yan, Wei Wang, Haifeng Wang*, and Fener Chen*. TfOH-Catalyzed Regioselective S–H Insertion of Cyclic Thioamide Derivatives with Diazo Compounds at Room Temperature. J. Org. Chem. leyu乐鱼, 88, 7, 4452-4457.

3. Zhewei Yan, Hangli He, Dabiao Yuan, Qiongjiao Yan, Wei Wang, Haipeng Jiang, Haifeng Wang*, Fener Chen*. Regioselective O-Alkylation of 2-Pyridones by TfOH-Catalyzed Carbenoid Insertion. Chem. Commun., leyu乐鱼, 59, 106-109.

4. Rui Wang, Hangli He, Qiongjiao Yan, Wei Wang, Haifeng Wang*, Fener Chen*. TfOH-Catalyzed Three-Component Synthesis of Dithiocarbamates from α-Diazoesters under Continuous Flow Conditions. J. Flow Chem., leyu乐鱼, 13, 1-8.

5. Hangli He, Zhewei Yan, Qiongjiao Yan, Wei Wang, Haifeng Wang*, Fener Chen*. Solvent Controlled Three-Component Reaction of Diazo Compounds for the Synthesis of Hydrazone Compounds under Br?nsted Acid Catalysis, New J. Chem., 2022, 46, 22513-22517.

6. Hangli He, Jingyu Yan, Jingru Jin, Zhewei Yan, Qiongjiao Yan, Wei Wang, Haipeng Jiang, Haifeng Wang*, Fener Chen*. TfOH-Catalyzed Regioselective N2-Alkylation of Indazoles with Diazo Compounds. Chem. Commun., 2022, 58, 6429-6432.

7. Bozhen Gong, Haibo Zhu,* Liu Yang, Haifeng Wang*, Qiangwen Fan, Zongbo Xie and Zhanggao Le*. Base-promoted synthesis of diarylsulfones from sulfonyl hydrazines and diaryliodonium salts. Org. Biomol. Chem. 2022, 20, 3501-3505.

8. 葛锐, 朱园园, 王海峰*, 古双喜*. 手性化合物绝对构型确定的方法与应用. 有机化学, 2021, 42, 424-433.

9. Haifeng Wang*, Xiangli Sun, Manman Hu, Xiaoyi Zhang, Lele Xie, Shuangxi Gu*. Bromination of α-diazo phenylacetate derivatives using cobalt (II) bromid, Advanced Synthesis & Catalysis 2020, 362, 3347-3351.

10. Haifeng Wang, Shuangxi Gu, Qiongjiao Yan, Li Ding, Fen-Er Chen*. Asymmetric catalysis in synthetic strategies for chiral benzothiazepines. Green Synthesis and Catalysis, 2020, 12-25.

11. Haifeng Wang*, Xiangli Sun, Shuangling Zhang,Guanglu Liu, Chunjie Wang, Lili Zhu, Hui Zhang. Efficient copper-catalyzed synthesis of substituted pyrazoles at room temperature. Synlett, 2018, 29, 2689-2692.

12. Haifeng Wang, Linjie Yan, Yan Wu, Fener Chen*. Chloramphenicol base chemistry. part 10: asymmetric synthesis of α-hydroxy chiral alcohols via intramolecular michael additions of γ?hydroxy-α, β-unsaturated enones with chloramphenicol base derived bifunctional urea organocatalyst. Tetrahedron. 2017, 73, 2793-2800.

13. Haifeng Wang, Linjie Yan, FangjunXiong, Yan Wu, Fener Chen*. New chloramphenicol Schiff base ligands for the titanium-mediated asymmetric aldol reaction of α, β-unsaturated aldehydes with diketene: a short synthesis of atorvastatin calcium. RSC Advances, 2016, 6, 75470-75477.

14. Haifeng Wang, Linjie Yan, Yan Wu, Yipei Lu, Fener Chen*. Asymmetric synthesis of vitamin D3 analogues: organocatalyticdesymmetrization approach toward the A?ring precursor of Calcifediol. Org. Lett. 2015, 17, 5452-5455.

 

 

 

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